Summary Article on Advanced Ulcer Treatments used in the Operating Room

Christopher L. Winters, DPM^∗

Abstract

“Debridement is important throughout the process. There’s a lot of discussion in the medical literature about the factors that contribute to chronic wounds or nonhealing wounds, high inflammatory cytokine burden, high bacterial content in the wounds, senescent wound cells, high MMPs.

If you have a wound that’s full of slough and dead tissue, it just contributes to this chronic inflammatory low activity wound.

If you simply debride these wounds, make sure they’re all perfused and debride them, you shift from a chronic nonhealing inflamed wound to an acute wound that doesn’t have those characteristics.

More aggressive techniques require this to be done in the O.R.”

For Full Text in the archived Journal of the American College of Clinical Wound Specialists: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161631/