Role of Hyaluronic Acid Treatment in the Prevention of Keloid Scarring

Andrea Hoffmann, PhD,a,b Jessica Lynn Hoing, MD,a Mackenzie Newman, MS,a and  Richard Simman, MD, FACS, FACCWSa,b,∗

Abstract

“Keloids are benign dermal scars characterized by enhanced growth factor signaling, hyperproliferation activity and reduced extracellular matrix (ECM) deposition of hyaluronic acid. Our hypothesis is that high molecular weight HA can be used to replenish HA deposition in keloids thereby normalizing the keloid fibroblast phenotype.”

For Full Text in the archived Journal of the American College of Clinical Wound Specialists: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054787/

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